Document Type

Article

Publication Date

10-2012

Publication Title

Synlett

Volume

23

Issue

16

First Page

2371

Last Page

2371

DOI

10.1055/s-0032-1317045

Keywords

allylation, electrophilic aromatic substitution, indium, metathesis, umpolung

Abstract

The products corresponding to the reactions of arenes and γ-carbonyl cations may be obtained by a one-pot, bicatalytic process involving InCl3-catalyzed arene allylation and cross metathesis with electron-deficient alkenes. The process is successful with electronically neutral and electron-rich arenes, and modestly Lewis basic donor groups are tolerated with an increase in InCl3 loading from 10 mol% to 15 mol%, and in one case, 20 mol%.

Funding Reference Number

NSERC

Comments

First published in Synlett, copyright © Georg Thieme Verlag, an imprint of Thieme Publishing. To access the final version, see DOI: 10.1055/s-0032-1317045 at https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0032-1317045.

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