Document Type

Article

Publication Date

10-2014

Publication Title

Synlett

Volume

25

Issue

17

First Page

2467

Last Page

2470

DOI

10.1055/s-0034-1379009 letter

Keywords

alkynes, total synthesis, carbocation, fused-ring systems, electrophilic aromatic substitution, transition metals

Abstract

The synthesis of the Cinnamomum homosesquiterpenoid tenuifolin has been accomplished by way of an intramolecular Nicholas reaction of the [Co2(CO)6] complex of an alkyne-substituted biaryl for construction of the seven-membered ring. The cyclization features the reaction of a nonactivated arene ring with the propargyldicobalt cation to give the dibenzocycloheptyne-Co2(CO)6.

Funding Reference Number

NSERC

Comments

First published in Synlett, copyright © Georg Thieme Verlag, an imprint of Thieme Publishing. To access the final version, see DOI: 10.1055/s-0034-1379009 at https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0034-1379009

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