Title

Annulation reactions toward bicyclic and tricyclic cycloheptyne dicobalt complexes.

Date of Award

2004

Degree Type

Thesis

Degree Name

M.Sc.

Department

Chemistry and Biochemistry

First Advisor

Green, J.

Keywords

Chemistry, Organic.

Rights

CC BY-NC-ND 4.0

Abstract

Cycloheptane containing molecules widely occur in nature; however, the methods for rapid synthesis of those type compounds are limited. This thesis focused on the annulation reactions toward fused ring systems bearing a cycloheptyne dicobalt complex. A series of benzocycloheptyne dicobalt complexes 58 have been synthesized from conjugated (Z) enyne acetate dicobalt complexes 59 by intramolecular Nicholas reactions. Fused [7,6,5] system 101 has also been obtained in a one-pot reaction via [4+3] cycloadditionlintramolecular trapping reaction. In addition, the progress in intramolecular [4+2] cycloaddition of complex 80 is discussed.