Date of Award

2011

Degree Type

Dissertation

Degree Name

Ph.D.

Department

Chemistry and Biochemistry

First Advisor

Mutus, Bulent (Chemistry and Biochemistry)

Keywords

Biochemistry.

Rights

CC BY-NC-ND 4.0

Abstract

Parallel plate flow chambers, simulating in vivo fluid shear stress, provide a real time insight into the dynamic process of platelet aggregation and investigation of endothelial cell response to shear stress. This thesis describes the design and validation of - 1) A simple parallel plate flow chamber to study effects of shear stress on endothelial cells. This flow chamber is easy to use, inexpensive and fast to manufacture as compared to the flow devices reported previously. Moreover, it...

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