Title

CAP1 expression is developmentally regulated in Xenopus

Document Type

Article

Publication Date

2002

Publication Title

Mechanisms of Development

Volume

113

Issue

2

First Page

211

Last Page

214

DOI

10.1016/S0925-4773(02)00033-3

Abstract

We have cloned and characterized a Xenopus member of the cyclase associated protein (CAP) gene family. xCAP1 is expressed as a maternal transcript, but is up-regulated prior to gastrulation and subsequently localizes to head mesenchyme, lens, otic vesicle, and trunk mesoderm including the pronephros. At different stages, the gene also appears to differentiate surface from deep (sensorial) ectoderm. As in Drosophila, Xenopus CAP1 is expressed in the developing eye, specifically in the differentiating lens. However, in distinction to Drosophila, Xenopus CAP1 does not express in periodically arrayed neural bands.

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