Psychosocial subtyping and brain metabolism in children with epilepsy.
Date of Award
Rourke, Byron P.,
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Past research has indicated that psychosocial dysfunction in children with epilepsy is a significant area of concern. Psychosocial functioning in children with epilepsy has typically been broadly defined in relation to various control groups. The present investigation provided a more multidimensional classification to examine psychosocial functioning in these children. In Study 1, behavioural ratings from the Personality Inventory for Children-Revised (PIC-R) were subjected to cluster analyses, yielding a psychosocial typology. Based on clinical scale elevations of the mean PIC-R profiles, the participants were classified into six subtypes of psychosocial functioning: Cognitive-Somatic, Cognitive-Internalized, Cognitive-Externalized, Cognitive-Social Isolation, Internalized Psychopathology, and Somatic Concern. A second study was conducted to examine the relation between PET indices of brain metabolism and the psychosocial subtypes derived in Study 1. The finding indicated that four of the psychosocial subtypes were differentiated from controls by decreased glucose metabolism in specific brain areas. The heterogeneity of psychosocial deficits in children with epilepsy and the possible neural substrate contributing to such pattern of deficits were discussed.Dept. of Psychology. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis2003 .C657. Source: Dissertation Abstracts International, Volume: 65-10, Section: B, page: 5453. Adviser: Byron P. Rourke. Thesis (Ph.D.)--University of Windsor (Canada), 2003.
Collins, David W., "Psychosocial subtyping and brain metabolism in children with epilepsy." (2003). Electronic Theses and Dissertations. 3232.