Date of Award
Health and environmental sciences, Psychology
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This study associated chemotherapy-related cognitive impairment with Psychosocial Adjustment and Quality of Life (QOL) in seventy-four colorectal cancer patients. Assessments included the Cambridge Neuropsychological Test Automated Battery (CANTAB), Psychosocial Adjustment to Illness Scale - Self Report Version (PAIS-SR), and Functional Assessment to Cancer Therapy - General Version (FACT-G). The sample consisted of 4 groups: A & C (stage III/high-risk II), with A assessed pre-chemotherapy and C post-chemotherapy; and groups B & D (stage I/II) who did not require chemotherapy, with B assessed post-operatively and D 6-months post-operatively. A statistically insignificant negative association was found between CANTAB and PAIS-SR results. The association between PAIS-SR and FACT-G was also negative, was highly significant, and indicates that as psychosocial adjustment improves, so does QOL. This study suggests that cognitive changes do not influence patients' relationships and functional roles, which are strongly associated with QOL.
Galica, Jacqueline, "The impact of cognitive dysfunction upon the non-metastatic colorectal cancer patient's psychosocial adjustment and quality of life" (2008). Electronic Theses and Dissertations. 8189.