Date of Award

2008

Publication Type

Thesis

Degree Name

M.Sc.

Department

Nursing

First Advisor

Debbie Kane

Keywords

Health and environmental sciences, Psychology

Rights

info:eu-repo/semantics/openAccess

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Abstract

This study associated chemotherapy-related cognitive impairment with Psychosocial Adjustment and Quality of Life (QOL) in seventy-four colorectal cancer patients. Assessments included the Cambridge Neuropsychological Test Automated Battery (CANTAB), Psychosocial Adjustment to Illness Scale - Self Report Version (PAIS-SR), and Functional Assessment to Cancer Therapy - General Version (FACT-G). The sample consisted of 4 groups: A & C (stage III/high-risk II), with A assessed pre-chemotherapy and C post-chemotherapy; and groups B & D (stage I/II) who did not require chemotherapy, with B assessed post-operatively and D 6-months post-operatively. A statistically insignificant negative association was found between CANTAB and PAIS-SR results. The association between PAIS-SR and FACT-G was also negative, was highly significant, and indicates that as psychosocial adjustment improves, so does QOL. This study suggests that cognitive changes do not influence patients' relationships and functional roles, which are strongly associated with QOL.

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