Date of Award
Magnetic resonance imaging, Pure phase encoding, Quantitative MRI
Magnetic Resonance Imaging (MRI) is a non-invasive medical imaging modality that provides excellent soft tissue contrast and resolution. Objects with high magnetic susceptibility distort the magnetic field, leading to severe artifacts in conventional MRI. It is very challenging to image around metal implants. Novel strategies may exploit the field distortion for spatial encoding. The magnetic field map is required in the development of these methods. A robust field map can also be employed to quantify high susceptibility particles that play a major role in cell tracking studies and hyperthermic treatment of cancers.
Pure phase encoding (PPE) techniques with short encoding times are largely immune to magnetic field inhomogeneity artifacts. Artifact-free MR images around titanium were acquired with PPE techniques, from which the magnetic field distribution was derived. The approach was extended to quantify iron microparticles and was compared with conventional MRI to demonstrate its superiority.
Bazzi, Layale, "Quantitative Magnetic Resonance Imaging Methodology Development" (2022). Electronic Theses and Dissertations. 8789.