Document Type

Article

Publication Date

1-28-2017

Publication Title

Journal of Biomedical Optics

Volume

22

Issue

1

First Page

015003-1

Last Page

015003-7

DOI

10.1117/1.JBO.22.1.015003

Keywords

optical coherence tomography; Fourier domain; refractive index; multilayer systems.

Abstract

We introduce a theoretical method for simultaneous measurement of refractive index and thickness of multilayer systems using Fourier domain optical coherence tomography (FD-OCT) without any auxiliary arrangement. The input data to the formalism are the FD-OCT measured optical path lengths (OPLs) and properly selected spectral components of FD-OCT interference spectrum. The outputs of the formalism can be affected significantly by uncertainty in measuring the OPLs. An optimization method is introduced to deal with the relatively large amount of uncertainty in measured OPLs and enhance the final results. Simulation result shows that by using the optimization method, indices can be extracted with the absolute error ≤0.001 for transparent biological samples having indices <1.55.

Comments

Work was published while author was at the University of Ottawa, Physics Department, 150 Louis Pasteur, Ottawa, Ontario K1N 6N5, Canada

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