Document Type
Article
Publication Date
2011
Publication Title
Biomedical Optics Express
Volume
2
Issue
6
First Page
1664
Last Page
1673
Abstract
Quantification of skin changes due to acanthosis nigricans (AN), a disorder common among insulin-resistant diabetic and obese individuals, was investigated using two optical techniques: diffuse reflectance spectroscopy (DRS) and colorimetry. Measurements were obtained from AN lesions on the neck and two control sites of eight AN patients. A principal component/discriminant function analysis successfully differentiated between AN lesion and normal skin with 87.7% sensitivity and 94.8% specificity in DRS measurements and 97.2% sensitivity and 96.4% specificity in colorimetry measurements. © 2011 Optical Society of America.
DOI
10.1364/BOE.2.001664
Recommended Citation
Devpura, S.; Pattamadilok, B.; Syed, Z.U.; Rehse, Steven; and Vemulapalli, P.. (2011). Critical comparison of diffuse reflectance spectroscopy and colorimetry as dermatological diagnostic tools for acanthosis nigricans: A chemometric approach. Biomedical Optics Express, 2 (6), 1664-1673.
https://scholar.uwindsor.ca/physicspub/18
Comments
This paper was published in Biomedical Optics Express and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://dx.doi.org/10.1364/BOE.2.001664. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law.