Pathomimetic avatars reveal divergent roles of microenvironment in invasive transition of ductal carcinoma in situ

Authors

Mansoureh Sameni
Dora Cavallo-Medved, University of WindsorFollow
Omar E. E. Franco
Anita Chalasani
Kyungmin Ji
Neha Aggarwal
Arulselvi Anbalagan
Xuequn Chen
Raymond R. Mattingly
Simon W. Hayward
Bonnie F. Sloane, University of Windsor

Document Type

Article

Publication Date

5-15-2017

Publication Title

Breast Cancer Research

Volume

19

Issue

1

Abstract

The breast tumor microenvironment regulates progression of ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC). However, it is unclear how interactions between breast epithelial and stromal cells can drive this progression and whether there are reliable microenvironmental biomarkers to predict transition of DCIS to IDC.

DOI

10.1186/s13058-017-0847-0

Comments

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Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Recommended Citation

Sameni, Mansoureh; Cavallo-Medved, Dora; E. Franco, Omar E.; Chalasani, Anita; Ji, Kyungmin; Aggarwal, Neha; Anbalagan, Arulselvi; Chen, Xuequn; Mattingly, Raymond R.; Hayward, Simon W.; and Sloane, Bonnie F., "Pathomimetic avatars reveal divergent roles of microenvironment in invasive transition of ductal carcinoma in situ" (2017). Breast Cancer Research, 19, 1.
https://scholar.uwindsor.ca/biologypub/108