Breast Cancer Research
The breast tumor microenvironment regulates progression of ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC). However, it is unclear how interactions between breast epithelial and stromal cells can drive this progression and whether there are reliable microenvironmental biomarkers to predict transition of DCIS to IDC.
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Sameni, Mansoureh; Cavallo-Medved, Dora; E. Franco, Omar E.; Chalasani, Anita; Ji, Kyungmin; Aggarwal, Neha; Anbalagan, Arulselvi; Chen, Xuequn; Mattingly, Raymond R.; Hayward, Simon W.; and Sloane, Bonnie F., "Pathomimetic avatars reveal divergent roles of microenvironment in invasive transition of ductal carcinoma in situ" (2017). Breast Cancer Research, 19, 1.