Effects of concommitant denervation and re-amputation through the regenerative forelimb outgrowth of Xenopus laevis froglets.
Document Type
Article
Publication Date
1986
Publication Title
Canadian Journal of Zoology
Volume
64
Issue
1
First Page
258
Last Page
262
Abstract
Normally innervated Xenopus laevis froglet forelimbs respond to amputational injury by forming a heteromorphic, cartilaginous spike outgrowth. However, denervation concomitant with amputation of the distal portion of a regenerate outgrowth performed at 1, 2, 3, 4, and 6 weeks after initial forelimb amputation resulted in the regression (resorption) of most, if not all, of the remaining portion of the regenerate tissues. These results indicate that, as in urodele amphibians, concomitantly denervated and amputated forelimb outgrowths of postmetamorphic froglets do not adjust sufficiently to denervation and fresh amputation to allow regeneration to recommence. Instead, progressive resorption of the remaining tissues of the regenerate occurs.
DOI
10.1139/z86-041
Recommended Citation
Liversage, R.A.; Crawford, Michael J.; and McLaughlin, D.S, "Effects of concommitant denervation and re-amputation through the regenerative forelimb outgrowth of Xenopus laevis froglets." (1986). Canadian Journal of Zoology, 64, 1, 258-262.
https://scholar.uwindsor.ca/biologypub/17
Comments
The final version of this article is available from NRC Research Press here: http://dx.doi.org/10.1139/z86-041.