Document Type
Article
Publication Date
11-20-2021
Publication Title
Free Radical Biology and Medicine
Volume
176
First Page
73
Keywords
Alpha-tocopherol, Lipid membranes, Neutron diffraction, Phospholipid bilayers, Vitamin E
Last Page
79
Abstract
Vitamin E was one of the last fat-soluble vitamins to be discovered. We provide here an historical review of the discovery and the increasingly more detailed understanding of the role of α-tocopherol both as an antioxidant and as a structural component of phospholipid bilayer membranes. Despite the detailed descriptions now available of the orientation, location, and dynamics of α-tocopherol in lipid bilayers, there are still gaps in our knowledge of the effect of α-tocopherol and its potential receptors than control gene transcription.
DOI
10.1016/j.freeradbiomed.2021.09.015
ISSN
08915849
E-ISSN
18734596
Recommended Citation
Atkinson, Jeffrey; Marquardt, Drew; DiPasquale, Mitchell; and Harroun, Thad. (2021). From fat to bilayers: Understanding where and how vitamin E works. Free Radical Biology and Medicine, 176, 73-79.
https://scholar.uwindsor.ca/chemistrybiochemistrypub/290
PubMed ID
34555454
