Analysis of Trisiloxane Phosphocholine Bilayers

Authors

Mark B. Frampton, Brock University
Drew Marquardt, Universitat Graz
Ilse Letofsky-Papst, Technische Universitat Graz
Georg Pabst, Universitat Graz
Paul M. Zelisko, Brock University

Document Type

Article

Publication Date

5-23-2017

Publication Title

Langmuir

Volume

33

Issue

20

First Page

4948

Last Page

4953

Abstract

We have synthesized unique siloxane phosphocholines and characterized their aggregates in aqueous solution. The siloxane phosphocholines form nearly monodisperse vesicles in aqueous solution without the need for secondary extrusion processes. The area/lipid, lipid volume, and bilayer thickness were determined from small-angle X-ray scattering experiments. The impetus for the spontaneous formation of unilamellar vesicles by these compounds is discussed.

DOI

10.1021/acs.langmuir.6b04162

ISSN

07437463

E-ISSN

15205827

Recommended Citation

Frampton, Mark B.; Marquardt, Drew; Letofsky-Papst, Ilse; Pabst, Georg; and Zelisko, Paul M.. (2017). Analysis of Trisiloxane Phosphocholine Bilayers. Langmuir, 33 (20), 4948-4953.
https://scholar.uwindsor.ca/chemistrybiochemistrypub/298

PubMed ID

28471667