Neutron diffraction and Vitamin E

Document Type

Conference Proceeding

Publication Date

1-1-2010

Publication Title

Journal of Physics: Conference Series

Volume

251

Issue

1

Abstract

It is generally accepted that neutron diffraction from model membrane systems is an effective biophysical technique for determining membrane structure. Here we describe an example of how deuterium labelling can elucidate the location of specific membrane soluble molecules, including a brief discussion of the technique itself. We show that deuterium labelled α-tocopherol sits upright in the bilayer, as might be expected, but at very different locations within the bilayer, depending on the degree of lipid chain unsaturation. © 2010 IOP Publishing Ltd.

DOI

10.1088/1742-6596/251/1/012039

ISSN

17426588

E-ISSN

17426596

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