Date of Award

2009

Publication Type

Master Thesis

Degree Name

M.Sc.

Department

Biological Sciences

Keywords

Biology, Neuroscience.

Supervisor

Zhang, Huiming (Biological Sciences)

Rights

info:eu-repo/semantics/openAccess

Abstract

The inferior colliculus plays a key role in auditory processing. In the current study I used the albino rat, Rattus norvegicus, as an animal model to investigate auditory responses in single neurons in the dorsomedial subdivision of the inferior colliculus (ICd). My results reveal that ICd neurons exhibit various temporal firing patterns and long and variable first spike latencies. These neurons displayed a variety of frequency-tuning curves. Both monotonic and non-monotonic rate-level functions were present in these neurons. ICd neurons displayed stimulus-specific adaptation by reducing the strength of firing during repetitive tone burst stimulation but restored their responses when the quality of sound was changed. Functional decortication changed the strength of firing in ICd neurons, suggesting these neurons were controlled by the auditory cortex. My results suggest that the ICd may provide a gating mechanism that helps the auditory system to selectively process novel sounds in the acoustic environment.

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