On scattered waves and lipid domains: Detecting membrane rafts with X-rays and neutrons

Authors

Drew Marquardt, Universitat Graz
Frederick A. Heberle, Oak Ridge National Laboratory
Jonathan D. Nickels, Oak Ridge National Laboratory
Georg Pabst, Universitat Graz
John Katsaras, Oak Ridge National Laboratory

Document Type

Article

Publication Date

1-1-2015

Publication Title

Soft Matter

Volume

11

Issue

47

First Page

9055

Last Page

9072

Abstract

In order to understand the biological role of lipids in cell membranes, it is necessary to determine the mesoscopic structure of well-defined model membrane systems. Neutron and X-ray scattering are non-invasive, probe-free techniques that have been used extensively in such systems to probe length scales ranging from angstroms to microns, and dynamics occurring over picosecond to millisecond time scales. Recent developments in the area of phase separated lipid systems mimicking membrane rafts will be presented, and the underlying concepts of the different scattering techniques used to study them will be discussed in detail.

DOI

10.1039/c5sm01807b

ISSN

1744683X

E-ISSN

17446848

Recommended Citation

Marquardt, Drew; Heberle, Frederick A.; Nickels, Jonathan D.; Pabst, Georg; and Katsaras, John. (2015). On scattered waves and lipid domains: Detecting membrane rafts with X-rays and neutrons. Soft Matter, 11 (47), 9055-9072.
https://scholar.uwindsor.ca/chemistrybiochemistrypub/313

PubMed ID

26428538